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Add CellML links #1

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MichaelClerx opened this issue Aug 25, 2024 · 2 comments
Open

Add CellML links #1

MichaelClerx opened this issue Aug 25, 2024 · 2 comments

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@MichaelClerx
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Go through full list, add PMR links where possible (with note on curation?)

@aminforouzandehmehr
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Dear Michael,

Some models that can be in the list:

2021 Forouzandehmehr Hi
Base: Paci 2020, Rice2008 | Original Matlab Code | Paper Forouzandehmehr M, Koivumäki JT, Hyttinen J, Paci M (2021), A mathematical model of hiPSC cardiomyocytes electromechanics
Modifications:

  • A new passive force accounting for inotropic effects of non-cardiomyocytes components in EHTs.

2022 Forouzandehmehr Hi
Base: Forouzandehmehr2021, Tran2017 | Original Matlab Code | Paper Forouzandehmehr M, Paci M, Koivumäki JT, Hyttinen J (2022), Altered contractility in mutation-specific hypertrophic cardiomyopathy: A mechano-energetic in silico study with pharmacological insights
Modifications:

  • Offering mechanoenergetic parameter identification to model MYH7R403Q HCM+Mavacamten, and dose-dependent effects of Blebbistatin and Omecamtiv mecarbil.

2024 Forouzandehmehr Hi
Base: Forouzandehmehr2022, Tran2017, Tran2009 | Original Matlab Code | Paper Forouzandehmehr M, Paci M, Hyttinen J, Koivumäki JT (2024), In silico study of the mechanisms of hypoxia and contractile dysfunction during ischemia and reperfusion of hiPSC cardiomyocytes
Modifications:

  • A new extracellular oxygen dynamics formulation, linking the cellular ionic and myofilament ATPase rate changes to extracellular and capillary level oxygen concentration.
  • Extending modeling approach to simulations of ischemia and Levosimendan mechanism of action.

Thank you!

@MichaelClerx
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Thank you!
I have added them to the list

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