From 9e065f8b0345e4f8041530cc03d2a7ce64d81a30 Mon Sep 17 00:00:00 2001 From: CEastwood <116108977+Caroline-99@users.noreply.github.com> Date: Tue, 17 Sep 2024 10:46:24 +0100 Subject: [PATCH] Fixes #2524 Added intercalated cell of salivary gland and striated cell of salivary gland (#2559) * Added two cell terms -Imported two uberon terms UBERON_0014727 and UBERON_0014729 -Added two cell types with textual and logical defs, synonyms and references * Update cl-edit.owl * GO terms imported and added to striated cell of salivary gland GO terms imported and added to striated cell of salivary gland * added synonyms * Update cl-edit.owl --------- Co-authored-by: Alida Avola <81253886+AvolaAmg@users.noreply.github.com> --- src/ontology/cl-edit.owl | 39 +- src/ontology/imports/go_terms.txt | 4 +- src/ontology/imports/merged_import.owl | 1276 +++++++++++++++++++++++- src/ontology/imports/uberon_terms.txt | 4 +- src/patterns/definitions.owl | 5 +- src/patterns/pattern.owl | 6 + 6 files changed, 1324 insertions(+), 10 deletions(-) diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl index 64948494c..4f6f5ed5d 100644 --- a/src/ontology/cl-edit.owl +++ b/src/ontology/cl-edit.owl @@ -3072,6 +3072,8 @@ Declaration(Class(obo:CL_4047051)) Declaration(Class(obo:CL_4047052)) Declaration(Class(obo:CL_4052001)) Declaration(Class(obo:CL_4052002)) +Declaration(Class(obo:CL_4052048)) +Declaration(Class(obo:CL_4052049)) Declaration(Class(obo:CP_0000000)) Declaration(Class(obo:CP_0000025)) Declaration(Class(obo:CP_0000027)) @@ -3085,18 +3087,21 @@ Declaration(Class(obo:D96882F1-8709-49AB-BCA9-772A67EA6C33)) Declaration(Class(obo:GO_0005903)) Declaration(Class(obo:GO_0031045)) Declaration(Class(obo:GO_0036053)) +Declaration(Class(obo:GO_0036376)) Declaration(Class(obo:GO_0042599)) Declaration(Class(obo:GO_0044316)) Declaration(Class(obo:GO_0070278)) Declaration(Class(obo:GO_0070483)) Declaration(Class(obo:GO_0097729)) Declaration(Class(obo:GO_0098594)) +Declaration(Class(obo:GO_1990573)) Declaration(Class(obo:NCBITaxon_4896)) Declaration(Class(obo:NCBITaxon_6157)) Declaration(Class(obo:NCBITaxon_6237)) Declaration(Class(obo:NCBITaxon_9789)) Declaration(Class(obo:PATO_0000405)) Declaration(Class(obo:PATO_0001377)) +Declaration(Class(obo:PATO_0001408)) Declaration(Class(obo:PATO_0001870)) Declaration(Class(obo:PATO_0001979)) Declaration(Class(obo:PATO_0002064)) @@ -3188,6 +3193,8 @@ Declaration(Class(obo:UBERON_0011949)) Declaration(Class(obo:UBERON_0012398)) Declaration(Class(obo:UBERON_0012399)) Declaration(Class(obo:UBERON_0012419)) +Declaration(Class(obo:UBERON_0014727)) +Declaration(Class(obo:UBERON_0014729)) Declaration(Class(obo:UBERON_0027368)) Declaration(Class(obo:UBERON_0027371)) Declaration(Class(obo:UBERON_8400006)) @@ -21997,7 +22004,7 @@ SubClassOf(obo:CL_0005011 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0046717)) # Class: obo:CL_0005012 (multi-ciliated epithelial cell) -AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") Annotation(oboInOwl:hasDbXref "PMID:28400610") Annotation(oboInOwl:hasDbXref "PMID:38032388") Annotation(oboInOwl:hasDbXref "PMID:30422572") obo:IAO_0000115 obo:CL_0005012 "A columnar/cuboidal epithelial cell with multiple motile cilia on its apical surface. These cells facilitate the movement of liquids such as mucus or cerebrospinal fluid across the epithelial surface.") +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") Annotation(oboInOwl:hasDbXref "PMID:28400610") Annotation(oboInOwl:hasDbXref "PMID:30422572") Annotation(oboInOwl:hasDbXref "PMID:38032388") obo:IAO_0000115 obo:CL_0005012 "A columnar/cuboidal epithelial cell with multiple motile cilia on its apical surface. These cells facilitate the movement of liquids such as mucus or cerebrospinal fluid across the epithelial surface.") AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0005012 "multi-ciliated cell"@en) AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_0005012 "multiciliated cell"@en) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005012 "multiciliated epithelial cell"@en) @@ -27994,6 +28001,7 @@ AnnotationAssertion(oboInOwl:hasDbXref obo:CL_1001596 "CALOHA:TS-1282") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CALOHA:TS-1282") oboInOwl:hasRelatedSynonym obo:CL_1001596 "salivary gland glandular cells") AnnotationAssertion(rdfs:label obo:CL_1001596 "salivary gland glandular cell") EquivalentClasses(obo:CL_1001596 ObjectIntersectionOf(obo:CL_0000150 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001044))) +SubClassOf(obo:CL_1001596 obo:CL_0009005) SubClassOf(obo:CL_1001596 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0004809)) # Class: obo:CL_1001597 (seminal vesicle glandular cell) @@ -32450,6 +32458,35 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9067520") Annotation(obo AnnotationAssertion(rdfs:label obo:CL_4052002 "syncytial cell") EquivalentClasses(obo:CL_4052002 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0001908) ObjectSomeValuesFrom(obo:RO_0000056 obo:GO_0000768))) +# Class: obo:CL_4052048 (intercalated cell of salivary gland) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.") +AnnotationAssertion(terms:contributor obo:CL_4052048 ) +AnnotationAssertion(terms:contributor obo:CL_4052048 ) +AnnotationAssertion(terms:date obo:CL_4052048 "2024-09-11T09:55:55Z"^^xsd:dateTime) +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37724716") oboInOwl:hasBroadSynonym obo:CL_4052048 "intercalated duct cell") +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37724716") oboInOwl:hasExactSynonym obo:CL_4052048 "salivary intercalated duct cells") +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:35799078") oboInOwl:hasRelatedSynonym obo:CL_4052048 "Id cell") +AnnotationAssertion(rdfs:label obo:CL_4052048 "intercalated cell of salivary gland") +SubClassOf(obo:CL_4052048 obo:CL_1001596) +SubClassOf(obo:CL_4052048 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0014727)) +SubClassOf(obo:CL_4052048 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0015766)) + +# Class: obo:CL_4052049 (striated cell of salivary gland) + +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:34147989") Annotation(oboInOwl:hasDbXref "PMID:36726292") obo:IAO_0000115 obo:CL_4052049 "An columnar/cuboidal epithelial cell that is part of the striated duct of salivary gland, characterized by basal striations formed by infoldings of the plasma membrane. This cell play a crucial role in modifying the electrolyte composition and concentration of saliva through active ion transport, particularly the absorption of sodium and secretion of potassium.") +AnnotationAssertion(terms:contributor obo:CL_4052049 ) +AnnotationAssertion(terms:contributor obo:CL_4052049 ) +AnnotationAssertion(terms:date obo:CL_4052049 "2024-09-11T10:00:25Z"^^xsd:dateTime) +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11590591") oboInOwl:hasBroadSynonym obo:CL_4052049 "SD cells") +AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:11590591") oboInOwl:hasBroadSynonym obo:CL_4052049 "striated duct cells") +AnnotationAssertion(rdfs:label obo:CL_4052049 "striated cell of salivary gland") +EquivalentClasses(obo:CL_4052049 ObjectIntersectionOf(obo:CL_0000075 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0014729))) +SubClassOf(obo:CL_4052049 obo:CL_1001596) +SubClassOf(obo:CL_4052049 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0015766)) +SubClassOf(obo:CL_4052049 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0036376)) +SubClassOf(obo:CL_4052049 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_1990573)) + # Class: obo:CP_0000000 (obsolete CP:0000000) AnnotationAssertion(obo:IAO_0100001 obo:CP_0000000 obo:CL_0017500) diff --git a/src/ontology/imports/go_terms.txt b/src/ontology/imports/go_terms.txt index ed9112049..2d8c21efd 100644 --- a/src/ontology/imports/go_terms.txt +++ b/src/ontology/imports/go_terms.txt @@ -9,4 +9,6 @@ GO:0099096 GO:0004990 GO:0070278 GO:0000279 -GO:0036053 \ No newline at end of file +GO:0036053 +GO:0036376 +GO:1990573 diff --git a/src/ontology/imports/merged_import.owl b/src/ontology/imports/merged_import.owl index 9ed12be40..77e2a5c2e 100644 --- a/src/ontology/imports/merged_import.owl +++ b/src/ontology/imports/merged_import.owl @@ -7,8 +7,8 @@ Prefix(rdfs:=) Ontology( - -Annotation(owl:versionInfo "2024-09-06") + +Annotation(owl:versionInfo "2024-09-13") Declaration(Class()) Declaration(Class()) @@ -71,6 +71,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -853,6 +855,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1288,6 +1291,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1481,6 +1485,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1637,6 +1643,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1651,6 +1659,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2082,6 +2091,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2243,6 +2254,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2259,7 +2272,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2646,6 +2662,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2788,6 +2805,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2853,6 +2871,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3127,6 +3146,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3281,6 +3301,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3382,6 +3404,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3415,6 +3438,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3481,6 +3506,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3737,6 +3763,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -4909,6 +4938,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -5766,6 +5797,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6223,6 +6255,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6277,6 +6310,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6338,6 +6372,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6438,6 +6473,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6688,6 +6726,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6735,6 +6776,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6856,6 +6900,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7012,6 +7059,12 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7106,10 +7159,16 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7606,6 +7665,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7733,6 +7793,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -7851,6 +7912,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -8190,7 +8254,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11158,6 +11221,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -13111,6 +13177,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -14166,6 +14236,7 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -19510,6 +19581,16 @@ AnnotationAssertion( "regulation of heart rate") SubClassOf( ) +# Class: (regulation of sodium ion transport) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "regulation of Na+ transport") +AnnotationAssertion( "regulation of sodium transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002028") +AnnotationAssertion(rdfs:label "regulation of sodium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of L-glutamate import across plasma membrane) AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of L-glutamate import into a cell.") @@ -24647,6 +24728,16 @@ AnnotationAssertion(rdfs:label "glom EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (renal sodium ion transport) + +AnnotationAssertion(Annotation( "GOC:mtg_cardio") "The directed movement of sodium ions (Na+) by the renal system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003096") +AnnotationAssertion(rdfs:label "renal sodium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (renal water transport) AnnotationAssertion(Annotation( "GOC:mtg_cardio") "The directed movement of water (H2O) by the renal system.") @@ -27655,6 +27746,44 @@ AnnotationAssertion(rdfs:label "calc EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (potassium channel activity) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_transport") Annotation( "GOC:pr") Annotation( "ISBN:0815340729") "Enables the energy-independent facilitated diffusion of a potassium ion through a transmembrane aqueous pore or channel.") +AnnotationAssertion(Annotation(rdfs:label "Activation of ATP sensitive Potassium channels in neuroendocrine cells") "Reactome:R-HSA-1296024") +AnnotationAssertion(Annotation(rdfs:label "Activation of Ca2+ activated Potassium channels with Intermediate conductance") "Reactome:R-HSA-1296035") +AnnotationAssertion(Annotation(rdfs:label "Activation of Ca2+ activated Potassium channels with large conductance") "Reactome:R-HSA-1296037") +AnnotationAssertion(Annotation(rdfs:label "Activation of Ca2+ activated Potassium channels with small conductance") "Reactome:R-HSA-1296039") +AnnotationAssertion(Annotation(rdfs:label "Activation of TWIK-related K+ channel (TREK)") "Reactome:R-HSA-1296348") +AnnotationAssertion(Annotation(rdfs:label "Activation of THIK") "Reactome:R-HSA-1299297") +AnnotationAssertion(Annotation(rdfs:label "Activation of tandem pore domain in a weak inwardly rectifying K+ channels") "Reactome:R-HSA-1299304") +AnnotationAssertion(Annotation(rdfs:label "Activation of TASK") "Reactome:R-HSA-1299318") +AnnotationAssertion(Annotation(rdfs:label "Activation of TRESK") "Reactome:R-HSA-1299338") +AnnotationAssertion(Annotation(rdfs:label "Activation of TALK") "Reactome:R-HSA-1299359") +AnnotationAssertion(Annotation(rdfs:label "Slo3 Potassium Transport") "Reactome:R-HSA-2534365") +AnnotationAssertion(Annotation(rdfs:label "KCNK dimers transport K+ from cytosol to extracellular region") "Reactome:R-HSA-5578910") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0005267") +AnnotationAssertion(rdfs:label "potassium channel activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sodium channel activity) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_transport") Annotation( "GOC:pr") Annotation( "ISBN:0815340729") "Enables the energy-independent facilitated diffusion of a sodium ion through a transmembrane aqueous pore or channel.") +AnnotationAssertion(Annotation(rdfs:label "UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol") "Reactome:R-HSA-2730664") +AnnotationAssertion(Annotation(rdfs:label "TRPM4,5 transport extracellular Na+ to cytosol") "Reactome:R-HSA-3295580") +AnnotationAssertion(Annotation(rdfs:label "SCN3A:SCN2B,4B transports Na+ from the extracellular region to the cytosol") "Reactome:R-HSA-9717374") +AnnotationAssertion(Annotation(rdfs:label "SCN9A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol") "Reactome:R-HSA-9717382") +AnnotationAssertion(Annotation(rdfs:label "TRPM5 transports Na+ from the extracellular region to the cytosol") "Reactome:R-HSA-9717395") +AnnotationAssertion(Annotation(rdfs:label "SCN2A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol") "Reactome:R-HSA-9717396") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0005272") +AnnotationAssertion(rdfs:label "sodium channel activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (amine transmembrane transporter activity) AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0198506732") Annotation( "ISBN:0815340729") "Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.") @@ -29995,6 +30124,42 @@ AnnotationAssertion( "monoatomic cation transport") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (potassium ion transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-03T02:39:22Z") +AnnotationAssertion( "GO:0015458") +AnnotationAssertion( "GO:0071804") +AnnotationAssertion( "sodium/potassium transport") +AnnotationAssertion( "cellular potassium ion transport") +AnnotationAssertion( "potassium conductance") +AnnotationAssertion( "potassium ion conductance") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "K+ conductance") +AnnotationAssertion(Annotation( "GOC:mah") "low voltage-dependent potassium channel auxiliary protein activity") +AnnotationAssertion(Annotation( "GOC:mah") "low voltage-gated potassium channel auxiliary protein activity") +AnnotationAssertion( "potassium transport") +AnnotationAssertion( "GO:0006813") +AnnotationAssertion(rdfs:label "potassium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sodium ion transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "GO:0006834") +AnnotationAssertion( "GO:0016974") +AnnotationAssertion( "sodium/potassium transport") +AnnotationAssertion( "sodium transport") +AnnotationAssertion( "mitochondrial sodium/calcium ion exchange") +AnnotationAssertion( "sodium:calcium exchange") +AnnotationAssertion( "sodium:solute transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "sodium channel auxiliary protein activity") +AnnotationAssertion( "GO:0006814") +AnnotationAssertion(rdfs:label "sodium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (calcium ion transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -30149,6 +30314,17 @@ AnnotationAssertion( "intracellular iron ion homeostasis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (intracellular sodium ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell.") +AnnotationAssertion( "cellular sodium ion homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006883") +AnnotationAssertion(rdfs:label "intracellular sodium ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (cell volume homeostasis) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.") @@ -35420,6 +35596,22 @@ AnnotationAssertion( "negative regulation of fibroblast migration") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (positive regulation of sodium ion transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010765") +AnnotationAssertion(rdfs:label "positive regulation of sodium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of sodium ion transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010766") +AnnotationAssertion(rdfs:label "negative regulation of sodium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (positive regulation of cell morphogenesis) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.") @@ -37064,6 +37256,36 @@ AnnotationAssertion(rdfs:label "prot EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (potassium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of potassium ions (K+) from one side of a membrane to the other.") +AnnotationAssertion( "GO:0015388") +AnnotationAssertion( "GO:0022817") +AnnotationAssertion( "RHEA:29463") +AnnotationAssertion( "potassium transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "potassium uptake permease activity") +AnnotationAssertion( "potassium uptake transmembrane transporter activity") +AnnotationAssertion( "GO:0015079") +AnnotationAssertion(rdfs:label "potassium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sodium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:ai") Annotation( "RHEA:34963") "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24076"^^xsd:anyURI) +AnnotationAssertion( "GO:0022816") +AnnotationAssertion( "RHEA:34963") +AnnotationAssertion( "sodium transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015081") +AnnotationAssertion(rdfs:label "sodium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (calcium ion transmembrane transporter activity) AnnotationAssertion(Annotation( "GOC:dgf") Annotation( "RHEA:29671") "Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.") @@ -37330,6 +37552,17 @@ AnnotationAssertion( "channel activity") SubClassOf( ) +# Class: (calcium-activated potassium channel activity) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_transport") "Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24605"^^xsd:anyURI) +AnnotationAssertion(Annotation(rdfs:label "KCNN2 transports K+ from the cytosol to the extracellular region") "Reactome:R-HSA-9663752") +AnnotationAssertion(Annotation(rdfs:label "KCNMA1:KCNMB1 transports potassium ions from the cytosol to the extracellular region") "Reactome:R-HSA-9667809") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015269") +AnnotationAssertion(rdfs:label "calcium-activated potassium channel activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (ligand-gated monoatomic ion channel activity) AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.") @@ -37345,6 +37578,29 @@ AnnotationAssertion( "ligand-gated monoatomic ion channel activity") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +# Class: (kainate selective glutamate receptor activity) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:10049997") Annotation( "PMID:8804111") "An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015277") +AnnotationAssertion(rdfs:comment "Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'ionotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'.") +AnnotationAssertion(rdfs:label "kainate selective glutamate receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ligand-gated sodium channel activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.") +AnnotationAssertion(Annotation(rdfs:label "SCNN channels transport extracellular Na+ to cytosol") "Reactome:R-HSA-2672334") +AnnotationAssertion(Annotation( "GOC:fj") "ASIC activity") +AnnotationAssertion(Annotation( "GOC:fj") "acid-sensing ion channel activity") +AnnotationAssertion(Annotation( "GOC:fj") "amiloride-sensitive sodium channel activity") +AnnotationAssertion(Annotation( "GOC:fj") "epithelial sodium channel") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015280") +AnnotationAssertion(rdfs:label "ligand-gated sodium channel activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (secondary active transmembrane transporter activity) AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0198506732") Annotation( "ISBN:0815340729") Annotation( "PMID:10839820") "Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters.") @@ -41903,6 +42159,18 @@ AnnotationAssertion( "intracellular monoatomic cation homeostasis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (intracellular potassium ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of potassium ions within a cell.") +AnnotationAssertion( "GO:0017079") +AnnotationAssertion( "cellular potassium ion homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030007") +AnnotationAssertion(rdfs:label "intracellular potassium ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (establishment of cell polarity) AnnotationAssertion(Annotation( "GOC:mah") "The specification and formation of anisotropic intracellular organization or cell growth patterns.") @@ -43657,6 +43925,15 @@ AnnotationAssertion(rdfs:label "esta SubClassOf( ) SubClassOf( ) +# Class: (potassium ion binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a potassium ion (K+).") +AnnotationAssertion( "K ion binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0030955") +AnnotationAssertion(rdfs:label "potassium ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (intraciliary transport particle) AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "PMID:14570576") Annotation( "PMID:22118932") Annotation( "PMID:23945166") "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.") @@ -44510,6 +44787,15 @@ AnnotationAssertion( "positive regulation of protein modification process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (sodium ion binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a sodium ion (Na+).") +AnnotationAssertion( "Na+ ion binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0031402") +AnnotationAssertion(rdfs:label "sodium ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (carboxylic acid binding) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-).") @@ -48133,6 +48419,15 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (kainate selective glutamate receptor complex) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:18655795") "An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0032983") +AnnotationAssertion(rdfs:label "kainate selective glutamate receptor complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (protein-containing complex disassembly) AnnotationAssertion(Annotation( "GOC:mah") "The disaggregation of a protein-containing macromolecular complex into its constituent components.") @@ -49868,6 +50163,24 @@ AnnotationAssertion(rdfs:label "calc EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (potassium channel complex) + +AnnotationAssertion(Annotation( "GOC:mah") "An ion channel complex through which potassium ions pass.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0034705") +AnnotationAssertion(rdfs:label "potassium channel complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sodium channel complex) + +AnnotationAssertion(Annotation( "GOC:mah") "An ion channel complex through which sodium ions pass.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0034706") +AnnotationAssertion(rdfs:label "sodium channel complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (iron ion transmembrane transport) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:11390404") "A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.") @@ -51059,6 +51372,20 @@ AnnotationAssertion(rdfs:label "T-he EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (sodium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:vw") "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-10T02:52:36Z") +AnnotationAssertion( "sodium ion membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035725") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "sodium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (hepatic stellate cell activation) AnnotationAssertion(Annotation( "CL:0000632") Annotation( "GOC:bf") "A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.") @@ -51464,6 +51791,30 @@ EquivalentClasses( ObjectIntersection SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (response to potassium ion) + +AnnotationAssertion(Annotation( "GOC:yaf") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-25T02:58:45Z") +AnnotationAssertion(Annotation( "GOC:bf") "response to K+ ion") +AnnotationAssertion(Annotation( "GOC:bf") "response to potassium") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035864") +AnnotationAssertion(rdfs:label "response to potassium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to potassium ion) + +AnnotationAssertion(Annotation( "GOC:yaf") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-25T02:59:11Z") +AnnotationAssertion(Annotation( "GOC:bf") "cellular response to K+ ion") +AnnotationAssertion(Annotation( "GOC:bf") "cellular response to potassium") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035865") +AnnotationAssertion(rdfs:label "cellular response to potassium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (ciliary transition zone) AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "PMID:21422230") "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.") @@ -52269,6 +52620,21 @@ AnnotationAssertion(rdfs:label "plat EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (sodium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:14674689") "The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-16T11:13:55Z") +AnnotationAssertion( "GO:0071436") +AnnotationAssertion( "GO:0098667") +AnnotationAssertion( "sodium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "sodium export") +AnnotationAssertion( "sodium ion export") +AnnotationAssertion( "GO:0036376") +AnnotationAssertion(rdfs:label "sodium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (myofilament) AnnotationAssertion(Annotation( "Wikipedia:Myofilament") "Any of the smallest contractile units of a myofibril (striated muscle fiber).") @@ -55542,6 +55908,55 @@ AnnotationAssertion( "extracellular non-membrane-bounded organelle") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of potassium ion transport) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "regulation of K+ transport") +AnnotationAssertion( "regulation of potassium transport") +AnnotationAssertion( "regulation of K+ conductance") +AnnotationAssertion( "regulation of potassium conductance") +AnnotationAssertion( "regulation of potassium ion conductance") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043266") +AnnotationAssertion(rdfs:label "regulation of potassium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of potassium ion transport) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of potassium ion transport") +AnnotationAssertion( "down-regulation of potassium ion transport") +AnnotationAssertion( "downregulation of potassium ion transport") +AnnotationAssertion( "negative regulation of K+ transport") +AnnotationAssertion( "negative regulation of potassium transport") +AnnotationAssertion( "inhibition of potassium ion transport") +AnnotationAssertion( "negative regulation of potassium ion conductance") +AnnotationAssertion( "regulation of K+ conductance") +AnnotationAssertion( "regulation of potassium conductance") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "transmembrane conductance regulator activity") +AnnotationAssertion( "GO:0043267") +AnnotationAssertion(rdfs:label "negative regulation of potassium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of potassium ion transport) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "positive regulation of K+ transport") +AnnotationAssertion( "positive regulation of potassium transport") +AnnotationAssertion( "up regulation of potassium ion transport") +AnnotationAssertion( "up-regulation of potassium ion transport") +AnnotationAssertion( "upregulation of potassium ion transport") +AnnotationAssertion( "activation of potassium ion transport") +AnnotationAssertion( "positive regulation of K+ conductance") +AnnotationAssertion( "positive regulation of potassium conductance") +AnnotationAssertion( "positive regulation of potassium ion conductance") +AnnotationAssertion( "stimulation of potassium ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043268") +AnnotationAssertion(rdfs:label "positive regulation of potassium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of monoatomic ion transport) AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -70528,6 +70943,22 @@ AnnotationAssertion( "calcium ion homeostasis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (potassium ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055075") +AnnotationAssertion(rdfs:label "potassium ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sodium ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jid") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055078") +AnnotationAssertion(rdfs:label "sodium ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (monoatomic cation homeostasis) AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:jid") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom.") @@ -80462,6 +80893,25 @@ EquivalentClasses( ObjectIntersection SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (potassium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "A process in which a potassium ion is transported from one side of a membrane to the other.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-03T02:43:49Z") +AnnotationAssertion( "GO:0010163") +AnnotationAssertion( "potassium ion membrane transport") +AnnotationAssertion( "high affinity potassium ion import") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "high affinity potassium ion uptake") +AnnotationAssertion( "high-affinity potassium ion import") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "high-affinity potassium ion uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071805") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "potassium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (protein transmembrane transport) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "The process in which a protein is transported across a membrane.") @@ -85981,6 +86431,23 @@ AnnotationAssertion(rdfs:label "vacu EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (potassium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:11932440") "The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14265"^^xsd:anyURI) +AnnotationAssertion( "pr") +AnnotationAssertion( "2009-12-16T11:10:45Z") +AnnotationAssertion( "GO:0071435") +AnnotationAssertion( "GO:0098668") +AnnotationAssertion(Annotation( "GOC:mah") "potassium export") +AnnotationAssertion( "potassium ion export") +AnnotationAssertion( "potassium export across plasma membrane") +AnnotationAssertion( "potassium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097623") +AnnotationAssertion(rdfs:label "potassium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (distal tip cell migration) AnnotationAssertion(Annotation( "CL:0000661") Annotation( "GOC:mm2") Annotation( "PMID:24968003") "The orderly movement of a distal tip cell.") @@ -86620,6 +87087,21 @@ AnnotationAssertion( "L-glutamate import across plasma membrane") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +# Class: (sodium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-08-03T16:55:52Z") +AnnotationAssertion( "GO:0097369") +AnnotationAssertion( "GO:1990118") +AnnotationAssertion( "sodium import") +AnnotationAssertion( "sodium ion import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "sodium ion import") +AnnotationAssertion( "GO:0098719") +AnnotationAssertion(rdfs:label "sodium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (asymmetric stem cell division) AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:18513950") "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.") @@ -87238,6 +87720,15 @@ AnnotationAssertion(rdfs:label "G pr EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (kainate selective glutamate receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:signaling") Annotation( "ISBN:9780071120005") "The series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, ending with the regulation of a downstream cellular process, e.g. transcription.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098991") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "kainate selective glutamate receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (neuronal dense core vesicle) AnnotationAssertion(Annotation( "GOC:dos") Annotation( "ISBN:978-0-07-181001-2") Annotation( "Wikipedia:Neuropeptide&oldid=713905176") "A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.") @@ -88275,6 +88766,34 @@ AnnotationAssertion( "positive regulation of vesicle fusion with Golgi apparatus") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of kainate selective glutamate receptor signaling pathway) + +AnnotationAssertion(Annotation( "PMID:12597860") "Any process that modulates the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0106426") +AnnotationAssertion(rdfs:label "regulation of kainate selective glutamate receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of kainate selective glutamate receptor signaling pathway) + +AnnotationAssertion(Annotation( "PMID:12597860") "Any process that stops, prevents or reduces the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0106427") +AnnotationAssertion(rdfs:label "negative regulation of kainate selective glutamate receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of kainate selective glutamate receptor signaling pathway) + +AnnotationAssertion(Annotation( "PMID:12597860") "Any process that activates or increases the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23558"^^xsd:anyURI) +AnnotationAssertion( "hjd") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0106428") +AnnotationAssertion(rdfs:label "positive regulation of kainate selective glutamate receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of basement membrane organization) AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:27404358") "Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane.") @@ -91846,6 +92365,61 @@ AnnotationAssertion( "positive regulation of glycine import across plasma membrane") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of potassium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-06-15T01:13:49Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of potassium transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901016") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of potassium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of potassium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-06-15T01:14:10Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of potassium ion transmembrane transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of potassium transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of potassium ion transmembrane transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of potassium transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of potassium ion transmembrane transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of potassium transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of potassium transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of potassium transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of potassium ion transmembrane transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901017") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of potassium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (positive regulation of potassium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-06-15T01:14:18Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of potassium transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of potassium transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of potassium ion transmembrane transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of potassium transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of potassium ion transmembrane transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of potassium transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of potassium ion transmembrane transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of potassium transporter activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of potassium ion transmembrane transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901018") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of potassium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (regulation of calcium ion transmembrane transporter activity) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity.") @@ -92529,6 +93103,47 @@ SubClassOf( ) SubClassOf( ) +# Class: (regulation of potassium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-09-28T15:58:00Z") +AnnotationAssertion( "regulation of potassium ion membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901379") +AnnotationAssertion(rdfs:label "regulation of potassium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of potassium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-09-28T15:59:08Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of potassium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of potassium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of potassium ion transmembrane transport") +AnnotationAssertion( "negative regulation of potassium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of potassium ion transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901380") +AnnotationAssertion(rdfs:label "negative regulation of potassium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of potassium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-09-28T15:59:25Z") +AnnotationAssertion( "positive regulation of potassium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of potassium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of potassium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of potassium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of potassium ion transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901381") +AnnotationAssertion(rdfs:label "positive regulation of potassium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of chorionic trophoblast cell proliferation) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation.") @@ -94563,6 +95178,55 @@ AnnotationAssertion( "regulation of chromatin organization") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of sodium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "PMID:18591664") "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-07-18T13:33:53Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sodium ion membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902305") +AnnotationAssertion(rdfs:label "regulation of sodium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of sodium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "PMID:18591664") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-07-18T13:34:01Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902306") +AnnotationAssertion(rdfs:label "negative regulation of sodium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of sodium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "PMID:18591664") "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-07-18T13:34:18Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902307") +AnnotationAssertion(rdfs:label "positive regulation of sodium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of apoptotic process involved in morphogenesis) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sart") Annotation( "PMID:12202035") "Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis.") @@ -97451,6 +98115,134 @@ AnnotationAssertion( "multi-ciliated epithelial cell differentiation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of sodium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17095720") "Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-08-08T17:06:46Z") +AnnotationAssertion( "GO:1903273") +AnnotationAssertion( "regulation of sodium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sodium export") +AnnotationAssertion( "regulation of sodium ion export") +AnnotationAssertion( "GO:1903276") +AnnotationAssertion(rdfs:label "regulation of sodium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of sodium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17095720") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-08-08T17:10:22Z") +AnnotationAssertion( "GO:1903274") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion export from cell") +AnnotationAssertion( "negative regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sodium export") +AnnotationAssertion( "negative regulation of sodium ion export") +AnnotationAssertion( "GO:1903277") +AnnotationAssertion(rdfs:label "negative regulation of sodium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of sodium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17095720") "Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-08-08T17:10:30Z") +AnnotationAssertion( "GO:1903275") +AnnotationAssertion( "positive regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sodium export") +AnnotationAssertion( "positive regulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion export") +AnnotationAssertion( "GO:1903278") +AnnotationAssertion(rdfs:label "positive regulation of sodium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of potassium ion import) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:10636900") "Any process that modulates the frequency, rate or extent of potassium ion import.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-08-11T14:26:16Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of potassium import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of potassium ion uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903286") +AnnotationAssertion(rdfs:label "regulation of potassium ion import") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of potassium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:10636900") "Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-08-11T14:26:24Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of potassium import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of potassium ion import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of potassium ion uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of potassium import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of potassium ion import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of potassium ion uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of potassium import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of potassium ion import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of potassium ion uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of potassium import") +AnnotationAssertion( "negative regulation of potassium ion import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of potassium ion uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of potassium import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of potassium ion import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of potassium ion uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903287") +AnnotationAssertion(rdfs:label "negative regulation of potassium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of potassium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:10636900") "Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-08-11T14:26:32Z") +AnnotationAssertion( "positive regulation of potassium ion import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of potassium import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of potassium ion uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of potassium import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of potassium ion import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of potassium ion uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of potassium import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of potassium ion import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of potassium ion uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of potassium import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of potassium ion import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of potassium ion uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of potassium import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of potassium ion import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of potassium ion uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903288") +AnnotationAssertion(rdfs:label "positive regulation of potassium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (protein localization to Golgi membrane) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:11378902") "A process in which a protein is transported to, or maintained in, a location within a Golgi membrane.") @@ -98954,6 +99746,70 @@ AnnotationAssertion( "regulation of plasma membrane organization") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of potassium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:19646991") "Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-07-17T16:39:53Z") +AnnotationAssertion( "GO:1902302") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of potassium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of potassium export across plasma membrane") +AnnotationAssertion( "regulation of potassium ion export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903764") +AnnotationAssertion(rdfs:label "regulation of potassium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of potassium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:19646991") "Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-07-17T16:40:02Z") +AnnotationAssertion( "GO:1902303") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of potassium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of potassium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of potassium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of potassium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of potassium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of potassium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of potassium export") +AnnotationAssertion( "negative regulation of potassium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of potassium ion export across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of potassium ion export across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of potassium ion export across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of potassium ion export across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of potassium export") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of potassium ion export") +AnnotationAssertion( "GO:1903765") +AnnotationAssertion(rdfs:label "negative regulation of potassium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of potassium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:19646991") "Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-07-17T16:40:10Z") +AnnotationAssertion( "GO:1902304") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of potassium export") +AnnotationAssertion( "positive regulation of potassium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of potassium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of potassium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of potassium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of potassium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of potassium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of potassium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of potassium ion export across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of potassium ion export across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of potassium ion export across plasma membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of potassium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of potassium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of potassium ion export across plasma membrane") +AnnotationAssertion( "GO:1903766") +AnnotationAssertion(rdfs:label "positive regulation of potassium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (protein localization to vacuolar membrane) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:25378562") "A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.") @@ -99005,6 +99861,44 @@ AnnotationAssertion( "positive regulation of cardiac conduction") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of sodium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:19376779") "Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane.") +AnnotationAssertion( "nc") +AnnotationAssertion( "2015-01-07T16:48:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903782") +AnnotationAssertion(rdfs:label "regulation of sodium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of sodium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:19376779") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane.") +AnnotationAssertion( "nc") +AnnotationAssertion( "2015-01-07T16:48:51Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion import across plasma membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903783") +AnnotationAssertion(rdfs:label "negative regulation of sodium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of sodium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:19376779") "Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane.") +AnnotationAssertion( "nc") +AnnotationAssertion( "2015-01-07T16:49:00Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion import across plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion import across plasma membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903784") +AnnotationAssertion(rdfs:label "positive regulation of sodium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of amino acid transmembrane transport) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16115814") "Any process that modulates the frequency, rate or extent of amino acid transmembrane transport.") @@ -107924,6 +108818,20 @@ AnnotationAssertion(rdfs:label "dens EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (potassium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "PMID:9139127") "The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-12-04T09:48:12Z") +AnnotationAssertion( "GO:0010107") +AnnotationAssertion( "potassium import") +AnnotationAssertion( "potassium ion import") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "potassium ion uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1990573") +AnnotationAssertion(rdfs:label "potassium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (regulation of cytoplasmic translational termination) AnnotationAssertion(Annotation( "PMID:11570975") "Any process that modulates the frequency, rate or extent of cytoplasmic translational termination.") @@ -109447,6 +110355,17 @@ AnnotationAssertion(rdfs:label "posi EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of kainate selective glutamate receptor activity) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-01-18T10:14:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000312") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of kainate selective glutamate receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of T-helper 17 type immune response) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of T-helper 17 type immune response.") @@ -110789,6 +111708,45 @@ AnnotationAssertion( "positive regulation of stem cell proliferation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (regulation of sodium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-28T08:42:53Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of sodium transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000649") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of sodium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of sodium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-28T08:42:57Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of sodium transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000650") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of sodium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (positive regulation of sodium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-28T08:43:00Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of sodium transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000651") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of sodium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (regulation of cellular response to testosterone stimulus) AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus.") @@ -112526,6 +113484,7 @@ AnnotationAssertion( "NCBITaxon:1206794") AnnotationAssertion(rdfs:label "Ecdysozoa") SubClassOf( ) +DisjointClasses( ) # Class: (Lophotrochozoa) @@ -112547,6 +113506,7 @@ AnnotationAssertion(Annotation( "NCBITaxon:131209") AnnotationAssertion(rdfs:label "Zygnemophyceae") SubClassOf( ) +DisjointClasses( ) # Class: (Streptophytina) @@ -112618,6 +113578,7 @@ AnnotationAssertion( "NCBITaxon:1437180") AnnotationAssertion(rdfs:label "Acrogymnospermae") SubClassOf( ) +DisjointClasses( ) # Class: (Gnetidae) @@ -112737,6 +113698,8 @@ AnnotationAssertion(Annotation( "NCBITaxon:2") AnnotationAssertion(rdfs:label "Bacteria") SubClassOf( ) +DisjointClasses( ) +DisjointClasses( ) # Class: (Dictyosteliaceae) @@ -112809,6 +113772,7 @@ AnnotationAssertion(Annotation( "NCBITaxon:2157") AnnotationAssertion(rdfs:label "Archaea") SubClassOf( ) +DisjointClasses( ) # Class: (Rhabditina) @@ -112841,6 +113805,11 @@ AnnotationAssertion( "NCBITaxon:2611352") AnnotationAssertion(rdfs:label "Discoba") SubClassOf( ) +DisjointClasses( ) +DisjointClasses( ) +DisjointClasses( ) +DisjointClasses( ) +DisjointClasses( ) # Class: (Zygnematophycidae) @@ -112866,6 +113835,10 @@ AnnotationAssertion(Annotation( "NCBITaxon:2698737") AnnotationAssertion(rdfs:label "Sar") SubClassOf( ) +DisjointClasses( ) +DisjointClasses( ) +DisjointClasses( ) +DisjointClasses( ) # Class: (Eukaryota) @@ -112894,6 +113867,7 @@ AnnotationAssertion( "NCBITaxon:314145") AnnotationAssertion(rdfs:label "Laurasiatheria") SubClassOf( ) +DisjointClasses( ) # Class: (Euarchontoglires) @@ -112918,6 +113892,7 @@ AnnotationAssertion( "NCBITaxon:314147") AnnotationAssertion(rdfs:label "Glires") SubClassOf( ) +DisjointClasses( ) # Class: (Simiiformes) @@ -113035,6 +114010,9 @@ AnnotationAssertion(Annotation( "NCBITaxon:33090") AnnotationAssertion(rdfs:label "Viridiplantae") SubClassOf( ) +DisjointClasses( ) +DisjointClasses( ) +DisjointClasses( ) # Class: (Coniferophyta) @@ -113044,6 +114022,7 @@ AnnotationAssertion(Annotation( "NCBITaxon:3312") AnnotationAssertion(rdfs:label "Coniferophyta") SubClassOf( ) +DisjointClasses( ) # Class: (Opisthokonta) @@ -113054,6 +114033,8 @@ AnnotationAssertion(Annotation( "NCBITaxon:33154") AnnotationAssertion(rdfs:label "Opisthokonta") SubClassOf( ) +DisjointClasses( ) +DisjointClasses( ) # Class: (Metazoa) @@ -113066,6 +114047,7 @@ AnnotationAssertion(Annotation( "NCBITaxon:33208") AnnotationAssertion(rdfs:label "Metazoa") SubClassOf( ) +DisjointClasses( ) # Class: (Bilateria) @@ -113074,6 +114056,7 @@ AnnotationAssertion( "NCBITaxon:33213") AnnotationAssertion(rdfs:label "Bilateria") SubClassOf( ) +DisjointClasses( ) # Class: (Protostomia) @@ -113082,6 +114065,7 @@ AnnotationAssertion( "NCBITaxon:33317") AnnotationAssertion(rdfs:label "Protostomia") SubClassOf( ) +DisjointClasses( ) # Class: (Deuterostomia) @@ -113101,6 +114085,7 @@ AnnotationAssertion(Annotation( "NCBITaxon:33554") AnnotationAssertion(rdfs:label "Carnivora") SubClassOf( ) +DisjointClasses( ) # Class: (Alveolata) @@ -113213,6 +114198,7 @@ AnnotationAssertion(Annotation( "NCBITaxon:38254") AnnotationAssertion(rdfs:label "Glaucocystophyceae") SubClassOf( ) +DisjointClasses( ) # Class: (Murinae) @@ -113232,6 +114218,7 @@ AnnotationAssertion(Annotation( "NCBITaxon:40674") AnnotationAssertion(rdfs:label "Mammalia") SubClassOf( ) +DisjointClasses( ) # Class: (Neopterygii) @@ -113296,6 +114283,7 @@ AnnotationAssertion( "NCBITaxon:451866") AnnotationAssertion(rdfs:label "Taphrinomycotina") SubClassOf( ) +DisjointClasses( ) # Class: (Fungi) @@ -113520,6 +114508,7 @@ AnnotationAssertion(Annotation( "NCBITaxon:6231") AnnotationAssertion(rdfs:label "Nematoda") SubClassOf( ) +DisjointClasses( ) # Class: (Rhabditida) @@ -113589,6 +114578,7 @@ AnnotationAssertion(Annotation( "NCBITaxon:7586") AnnotationAssertion(rdfs:label "Echinodermata") SubClassOf( ) +DisjointClasses( ) # Class: (Chordata) @@ -113643,6 +114633,7 @@ AnnotationAssertion(Annotation( "NCBITaxon:7898") AnnotationAssertion(rdfs:label "Actinopterygii") SubClassOf( ) +DisjointClasses( ) # Class: (Sarcopterygii) @@ -113740,6 +114731,7 @@ AnnotationAssertion( "NCBITaxon:9479") AnnotationAssertion(rdfs:label "Platyrrhini") SubClassOf( ) +DisjointClasses( ) # Class: (Callitrichinae) @@ -185905,6 +186897,56 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (rectal salt gland) + +AnnotationAssertion(Annotation( "UBERON:cjm") Annotation( "http://www.briancoad.com/dictionary/complete%20dictionary.htm") "An evagination of the terminal portion of the intestine that is capable of secreting high concentrations of excess sodium chloride.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(Annotation( "http://www.briancoad.com/dictionary/complete%20dictionary.htm") "digitiform gland") +AnnotationAssertion(Annotation( "http://www.briancoad.com/dictionary/complete%20dictionary.htm") Annotation( ) "glandula rectalis") +AnnotationAssertion( "rectal gland") +AnnotationAssertion( "BTO:0001157") +AnnotationAssertion( "SCTID:80455007") +AnnotationAssertion( "uberon") +AnnotationAssertion( "UBERON:0004757") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "rectal salt gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (salt gland) + +AnnotationAssertion(Annotation( "Wikipedia:Salt_gland") "An organ for excreting excess salts. It is found in elasmobranchs, seabirds, and some reptiles.[WP].") +AnnotationAssertion( ) +AnnotationAssertion( "BTO:0001204") +AnnotationAssertion( "GAID:1235") +AnnotationAssertion( "MESH:D012491") +AnnotationAssertion( "Wikipedia:Salt_gland") +AnnotationAssertion( "uberon") +AnnotationAssertion( "UBERON:0004758") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "salt gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cranial salt gland) + +AnnotationAssertion(Annotation( "OBOL:automatic") "A salt gland located in the cranium or head region.") +AnnotationAssertion( "uberon") +AnnotationAssertion( "UBERON:0004759") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cranial salt gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (gland of anal canal) AnnotationAssertion(Annotation( "OBOL:automatic") Annotation( "Wikipedia:Anal_gland") "A gland that is part of an anal canal [Automatically generated definition].") @@ -198505,7 +199547,6 @@ AnnotationAssertion(rdfs:label " SubClassOf(Annotation( "XAO") ) SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf(Annotation( "XAO") ObjectSomeValuesFrom( )) # Class: (future trigeminal ganglion) @@ -219469,6 +220510,61 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (intercalated duct) + +AnnotationAssertion(Annotation( "http://www.siumed.edu/~dking2/intro/glands.htm") "A small duct which drains individual secretory units. These are usually inconspicuous, lined by a simple epithelium consisting of low cuboidal cells.") +AnnotationAssertion( "NCIT:C32820") +AnnotationAssertion( "UMLS:C1512817") +AnnotationAssertion( "uberon") +AnnotationAssertion( "secretory duct") +AnnotationAssertion( "UBERON:0014725") +AnnotationAssertion(rdfs:label "intercalated duct") +SubClassOf( ) + +# Class: (intercalated duct of pancreas) + +AnnotationAssertion(Annotation( "OBOL:automatic") "An intercalated duct that is part of a pancreas.") +AnnotationAssertion( ) +AnnotationAssertion( "FMA:16013") +AnnotationAssertion( "NCIT:C49267") +AnnotationAssertion( "SCTID:247520007") +AnnotationAssertion(Annotation( "FMA:16013") "ductus intercalatus (pancreas)") +AnnotationAssertion(Annotation( "FMA:16013") "pancreatic ductule") +AnnotationAssertion( "uberon") +AnnotationAssertion( "UBERON:0014726") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "intercalated duct of pancreas") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (intercalated duct of salivary gland) + +AnnotationAssertion(Annotation( "ncithesaurus:Intercalated_Duct_of_the_Salivary_Gland_System") "The tiny tubules with a very thin epithelial layer in the salivary glands running from the salivary acini into the striated duct.") +AnnotationAssertion( "FMA:60050") +AnnotationAssertion( "NCIT:C49266") +AnnotationAssertion( "uberon") +AnnotationAssertion( "UBERON:0014727") +AnnotationAssertion(rdfs:label "intercalated duct of salivary gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (striated duct of salivary gland) + +AnnotationAssertion(Annotation( "Wikipedia:Striated_duct") Annotation( "http://orcid.org/0000-0002-6601-2165") "Gland duct which connects an intercalated duct to an interlobular duct in a salivary gland.") +AnnotationAssertion( "FMA:60051") +AnnotationAssertion( "NCIT:C33635") +AnnotationAssertion( "UMLS:C1514993") +AnnotationAssertion( "uberon") +AnnotationAssertion( "UBERON:0014729") +AnnotationAssertion(rdfs:label "striated duct of salivary gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (palpebral vein) AnnotationAssertion(Annotation( "http://orcid.org/0000-0002-6601-2165") "A blood vessel that drains from from an eyelid.") @@ -229024,6 +230120,178 @@ DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ObjectComplementOf())) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) diff --git a/src/ontology/imports/uberon_terms.txt b/src/ontology/imports/uberon_terms.txt index 124784a98..e127eb66f 100644 --- a/src/ontology/imports/uberon_terms.txt +++ b/src/ontology/imports/uberon_terms.txt @@ -51,4 +51,6 @@ UBERON:0008198 UBERON:0004025 UBERON:0004903 UBERON:0004642 -UBERON:0006250 \ No newline at end of file +UBERON:0006250 +UBERON:0014727 +UBERON:0014729 \ No newline at end of file diff --git a/src/patterns/definitions.owl b/src/patterns/definitions.owl index 876c6fe42..440e8a95b 100644 --- a/src/patterns/definitions.owl +++ b/src/patterns/definitions.owl @@ -7,9 +7,8 @@ Prefix(rdfs:=) Ontology( - - -Annotation(owl:versionInfo "2024-09-09") + +Annotation(owl:versionInfo "2024-09-13") Declaration(Class()) Declaration(Class()) diff --git a/src/patterns/pattern.owl b/src/patterns/pattern.owl index 873e3e4d6..f84d0c449 100644 --- a/src/patterns/pattern.owl +++ b/src/patterns/pattern.owl @@ -32,6 +32,7 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -89,4 +90,9 @@ AnnotationAssertion(rdfs:label EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +AnnotationAssertion(Annotation( "xsd:string"^^xsd:string) "This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies to only to some subtypes and species, and so should not be considered definitional. + +xsd:string"^^xsd:string) +AnnotationAssertion( "ExtendedDescription"^^xsd:string) +AnnotationAssertion( "https://cellxgene.cziscience.com/cellguide/xsd:string"^^xsd:string) ) \ No newline at end of file