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Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)
A fibroblast located in the lamina propria of the intestinal mucosa, particularly in the small intestine. This cell expresses PDGFRα and CD81 and is negative for α-smooth muscle actin (α-SMA). This cell is positioned adjacent to myofibroblasts surrounding colonic crypts. It is capable of synthesizing extracellular matrix components and structural proteins such as collagen and elastin[PMID:36639348][PMID:36251739].
Please check that the term does not already exist by using the ontology search tool OLS:
https://www.ebi.ac.uk/ols4/ontologies/cl
Preferred term label
Lamina propria fibroblast (S1)
Synonyms (add reference(s), please)
S1 fibroblast [PMID:30270042]
Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)
A fibroblast located in the lamina propria of the intestinal mucosa, particularly in the small intestine. This cell expresses PDGFRα and CD81 and is negative for α-smooth muscle actin (α-SMA). This cell is positioned adjacent to myofibroblasts surrounding colonic crypts. It is capable of synthesizing extracellular matrix components and structural proteins such as collagen and elastin[PMID:36639348][PMID:36251739].
Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)
Fibroblast
Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)
Lamina propria of intestinal mucosa
Your ORCID
https://orcid.org/0009-0005-7919-4905
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