diff --git a/packages/volto/news/6153.internal b/packages/volto/news/6153.internal
new file mode 100644
index 0000000000..6c8fd1188e
--- /dev/null
+++ b/packages/volto/news/6153.internal
@@ -0,0 +1 @@
+Debounced searching for users and groups in the `User Group Membership` Control Panel. @pnicolli
diff --git a/packages/volto/src/components/manage/Controlpanels/Users/UserGroupMembershipListing.jsx b/packages/volto/src/components/manage/Controlpanels/Users/UserGroupMembershipListing.jsx
index 7c3559f6b9..4530107479 100644
--- a/packages/volto/src/components/manage/Controlpanels/Users/UserGroupMembershipListing.jsx
+++ b/packages/volto/src/components/manage/Controlpanels/Users/UserGroupMembershipListing.jsx
@@ -1,5 +1,5 @@
-import React, { useEffect, useState } from 'react';
-import { cloneDeep, uniqBy } from 'lodash';
+import React, { useEffect, useState, useMemo } from 'react';
+import { cloneDeep, uniqBy, debounce } from 'lodash';
 import { useIntl } from 'react-intl';
 import { useSelector, useDispatch, shallowEqual } from 'react-redux';
 import jwtDecode from 'jwt-decode';
@@ -114,25 +114,41 @@ const ListingTemplate = ({
     matrix_options = [];
   }
 
+  const debouncedListUsers = useMemo(
+    () =>
+      debounce((query_user, groups_filter, userLimit) => {
+        dispatch(
+          listUsers({
+            search: query_user,
+            groups_filter: groups_filter.map((el) => el.value),
+            limit: userLimit,
+          }),
+        );
+      }, 300),
+    [dispatch],
+  );
+
   useEffect(() => {
     // Get users.
     if (show_users) {
-      dispatch(
-        listUsers({
-          search: query_user,
-          groups_filter: groups_filter.map((el) => el.value),
-          limit: userLimit,
-        }),
-      );
+      debouncedListUsers(query_user, groups_filter, userLimit);
     }
-  }, [dispatch, query_user, groups_filter, show_users, userLimit]);
+  }, [debouncedListUsers, query_user, groups_filter, show_users, userLimit]);
+
+  const debouncedListGroups = useMemo(
+    () =>
+      debounce((query_group) => {
+        dispatch(listGroups(query_group));
+      }, 300),
+    [dispatch],
+  );
 
   useEffect(() => {
     // Get matrix groups.
     if (show_matrix_options) {
-      dispatch(listGroups(query_group));
+      debouncedListGroups(query_group);
     }
-  }, [dispatch, query_group, show_matrix_options, groups_filter]);
+  }, [debouncedListGroups, query_group, show_matrix_options]);
 
   const onSelectOptionHandler = (selectedvalue, checked, singleClick) => {
     singleClick = singleClick ?? false;
diff --git a/packages/volto/src/components/manage/Controlpanels/Users/UserGroupMembershipMatrix.jsx b/packages/volto/src/components/manage/Controlpanels/Users/UserGroupMembershipMatrix.jsx
index ca41f24f4f..371acfd32c 100644
--- a/packages/volto/src/components/manage/Controlpanels/Users/UserGroupMembershipMatrix.jsx
+++ b/packages/volto/src/components/manage/Controlpanels/Users/UserGroupMembershipMatrix.jsx
@@ -1,9 +1,9 @@
-import React, { useEffect, useState } from 'react';
+import React, { useEffect, useState, useMemo } from 'react';
 import { useSelector, useDispatch } from 'react-redux';
 import { useIntl } from 'react-intl';
 import { Checkbox, Form, Input } from 'semantic-ui-react';
 
-import { isEqual } from 'lodash';
+import { isEqual, debounce } from 'lodash';
 
 import { messages } from '@plone/volto/helpers';
 import { listGroups } from '@plone/volto/actions'; // getRegistry
@@ -38,12 +38,20 @@ const UserGroupMembershipMatrix = ({ many_users, many_groups }) => {
     });
   }
 
+  const debouncedListGroups = useMemo(
+    () =>
+      debounce((query_group_filter) => {
+        dispatch(listGroups('', query_group_filter));
+      }, 300),
+    [dispatch],
+  );
+
   useEffect(() => {
     // TODO fetch group for at least query_group_filter.length > 1?
     if (!many_groups || (many_groups && query_group_filter.length > 1)) {
-      dispatch(listGroups('', query_group_filter));
+      debouncedListGroups(query_group_filter);
     }
-  }, [dispatch, many_groups, query_group_filter]);
+  }, [debouncedListGroups, many_groups, query_group_filter]);
 
   const onReset = (event) => {
     // event.preventDefault();