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Fixes #2578
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- Added a new term
- Added textual and logical definition with extended description
- Added synonyms
- Added references
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Caroline-99 committed Sep 19, 2024
1 parent 2b2910b commit f5778d7
Showing 1 changed file with 15 additions and 0 deletions.
15 changes: 15 additions & 0 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -3073,6 +3073,7 @@ Declaration(Class(obo:CL_4047052))
Declaration(Class(obo:CL_4052001))
Declaration(Class(obo:CL_4052002))
Declaration(Class(obo:CL_4052003))
Declaration(Class(obo:CL_4052004))
Declaration(Class(obo:CL_4052048))
Declaration(Class(obo:CL_4052049))
Declaration(Class(obo:CP_0000000))
Expand Down Expand Up @@ -32470,6 +32471,20 @@ AnnotationAssertion(rdfs:label obo:CL_4052003 "intestinal villus capillary endot
EquivalentClasses(obo:CL_4052003 ObjectIntersectionOf(obo:CL_0002144 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001213)))
SubClassOf(obo:CL_4052003 ObjectSomeValuesFrom(obo:RO_0000053 obo:PATO_0002064))

# Class: obo:CL_4052004 (intestinal fibroblastic reticular cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33707780") Annotation(oboInOwl:hasDbXref "doi:/10.1038/s41467-022-29734-2") obo:IAO_0000115 obo:CL_4052004 "A specialized fibroblastic reticular cell that is part of gut-associated lymphoid tissues(GALT), responsible for forming a structural network that facilitates immune cell interactions. This cell is found in Peyer's patches, cryptopatches, and isolated lymphoid follicles. It plays crucial roles in maintaining intestinal immunity by controlling innate lymphoid cell homeostasis and function, organizing lymphoid structures, and contributing to intestinal microbiome balance.")
AnnotationAssertion(terms:contributor obo:CL_4052004 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052004 "2024-09-19T11:22:18Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33707780") Annotation(oboInOwl:hasDbXref "doi:/10.1038/s41467-022-29734-2") terms:description obo:CL_4052004 "Intestinal fibroblastic reticular cells (FRCs) develop from both perivascular and subepithelial progenitors during Peyer's patch formation. Intestinal fibroblastic reticular cells express key markers such as CCL19, CCL21, CXCL13, TNFSF13B (also known as BAFF), and produce IL-7, which are important for their immune regulatory functions and the organization of lymphoid structures.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1038/s41467-022-29734-2") oboInOwl:hasNarrowSynonym obo:CL_4052004 "Ccl19-expressing FRCs")
AnnotationAssertion(Annotation(rdfs:comment "doi:/10.1038/s41467-022-29734-2") oboInOwl:hasNarrowSynonym obo:CL_4052004 "solitary intestinal lymphoid tissue (SILT) FRCs")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1038/s41467-022-29734-2") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4052004 "FRC")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:/10.1038/s41467-022-29734-2") oboInOwl:hasRelatedSynonym obo:CL_4052004 "gut-associated secondary lymphoid organs (SLOs) FRCs")
AnnotationAssertion(rdfs:label obo:CL_4052004 "intestinal fibroblastic reticular cell")
SubClassOf(obo:CL_4052004 obo:CL_0009101)
SubClassOf(obo:CL_4052004 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001962))

# Class: obo:CL_4052048 (intercalated cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.")
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