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NTR-astrocyte-restricted-precursor-and-neuronal-restricted-precursor #2512

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29 changes: 29 additions & 0 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -3062,6 +3062,8 @@ Declaration(Class(obo:CL_4042017))
Declaration(Class(obo:CL_4042018))
Declaration(Class(obo:CL_4042019))
Declaration(Class(obo:CL_4042020))
Declaration(Class(obo:CL_4042021))
Declaration(Class(obo:CL_4042022))
Declaration(Class(obo:CL_4047006))
Declaration(Class(obo:CL_4047007))
Declaration(Class(obo:CL_4047011))
Expand Down Expand Up @@ -32340,6 +32342,33 @@ SubClassOf(obo:CL_4042020 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_000625
SubClassOf(obo:CL_4042020 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000007479))
SubClassOf(obo:CL_4042020 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000007489))

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# Class: obo:CL_4042021 (neuronal-restricted precursor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10467245") obo:IAO_0000115 obo:CL_4042021 "A progenitor cell of the central nervous system that differentiates exclusively onto neurons. This progenitor cell is found in a hippocampus subventricular zone, developing cortex and spinal cord of the central nervous system.")
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AnnotationAssertion(terms:contributor obo:CL_4042021 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042021 "2024-09-02T11:42:12Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:SynonymTypeProperty obo:OMO_0003000) Annotation(oboInOwl:hasDbXref "PMID:12429182") oboInOwl:hasRelatedSynonym obo:CL_4042021 "NRP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9354325") Annotation(oboInOwl:hasDbXref "PMID:12429182") rdfs:comment obo:CL_4042021 "In vitro cultures of embryonic mouse neural tubes show that neuronal-restricted precursors (NRPs) are derived from multipotent neuroepithelial cells to give rise to neurons. This progression suggests a linear relationship between multipotent progenitors and neuronal-restricted differentiation. (Mayer-Proschel et al., 1997). In the spinal cord of rats, neural-restricted precursor cells give rise cholinergic, GABAergic, glutametergic neurons (Cao and Howard et al., 2002).")
AnnotationAssertion(rdfs:label obo:CL_4042021 "neuronal-restricted precursor"@en)
SubClassOf(obo:CL_4042021 obo:CL_0000123)
SubClassOf(obo:CL_4042021 obo:CL_0011026)
SubClassOf(obo:CL_4042021 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))

# Class: obo:CL_4042022 (astrocyte-restricted precursor)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:15531362") Annotation(oboInOwl:hasDbXref "PMID:33052610") obo:IAO_0000115 obo:CL_4042022 "A progenitor cell of the central nervous system that differentiates exclusively onto astrocytes. This progenitor cell expresses CD44 and S100 calcium-binding protein B.")
AnnotationAssertion(terms:contributor obo:CL_4042022 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042022 "2024-09-02T11:44:45Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:SynonymTypeProperty obo:OMO_0003000) Annotation(oboInOwl:hasDbXref "PMID:33052610") oboInOwl:hasRelatedSynonym obo:CL_4042022 "ARP")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33052610") oboInOwl:hasRelatedSynonym obo:CL_4042022 "astrocyte precursor cell")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33052610") rdfs:comment obo:CL_4042022 "In vitro, this progenitor cell can differentiate from glial-restricted precursor cells.")
AnnotationAssertion(rdfs:label obo:CL_4042022 "astrocyte-restricted precursor"@en)
SubClassOf(obo:CL_4042022 obo:CL_0000123)
SubClassOf(obo:CL_4042022 obo:CL_0011026)
SubClassOf(obo:CL_4042022 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001017))
SubClassOf(obo:CL_4042022 ObjectSomeValuesFrom(obo:RO_0002203 obo:CL_0000127))
SubClassOf(obo:CL_4042022 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000001307))

# Class: obo:CL_4047006 (fetal artery endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_4047006 "An endothelial cell that lines an artery in the fetal circulatory system.")
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