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A R package to create a score for in utero exposure to maternal smoking, based on whole blood DNA methylation.

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sebrauschert/DNAsmokeR

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DNAsmokeR package

This package is based on the paper by

Rauschert S, Melton PE, Heiskala A, Karhunen V, Burdge G, Craig JM, Godfrey KM, Lillycrop K, Mori TA, Beilin LJ, Oddy WH, Pennell C, Jaervelin MR, Sebert S, Huang RC. Cross-Continent Poly-DNA Methylation Score for Fetal Exposure to Maternal Smoking, developed in adolescents with Machine Learning Methods. in preparation.

It contains a function to create a whole blood DNA methylation in utero exposure score to maternal smoking during pregnancy.

Installation

This package can be installed in its BETA version by typing the following into the R console:

devtools::install_github("Hobbeist/DNAsmokeR", build_vignettes=T)

Functions

This package currently contains four functions:

  • smokeScore()
  • scoreMatrix()
  • boxplotScore() , and
  • shinySmokeR()

More details on these functions can be found in the vignette of this package and in the help pages in R.

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A R package to create a score for in utero exposure to maternal smoking, based on whole blood DNA methylation.

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